| SPEARS | Screener Proficiency Evaluation and Report System 
| Others |
| SPEARS | Shuttle Processing Electronic Archival & Retrieval System
| Others |
| SPEARS | Sorbent Polymer Extraction And Remediation System
| Others |
| SPEARS | Space Plasma Environment And Radio Science
| Others |
| SPEARS | Spill Planning Exercise and Response System
| Others |
| SPEARS | Supplier Performance Evaluation And Rating System
| Others |