| SOPHIA | Saipan Outdoor Physical Health Invigorating Adventure 
| Others |
| SOPHIA | Services Optimization Predictivity Human Innovation Analysis
| Others |
| SOPHIA | Simulations Of Photo Hadronic Interactions in Astrophysics
| Others |
| SOPHIA | Society Of Practitioners Of Health Impact Assessment
| Others |
| SOPHIA | Speak Out Play Havoc And Imagine Alternatives
| Others |
| SOPHIA | Speak Out Play Havoc Invite Alternatives
| Others |
| SOPHIA | Statewide Online Pleading Help and Information Assistant
| Others |