| SME | Lake Cumberland Regional Airport 
| Others |
| SME | Sales and Marketing Executives, Incorporated
| Others |
| SME | Scale Model Engineering
| Others |
| SME | Scale Model Equipment
| Others |
| SME | School of Medical Education
| Others |
| SME | Scout Mountain Equipment
| Others |
| SME | Search Marketing Engineer
| Others |
| SME | Secure Memory Encryption
| Others |
| SME | Security Management Entity
| Others |
| SME | Selling and Managing Employee
| Others |
| SME | Senior Mining Engineer
| Others |
| SME | Service Management Engine
| Others |
| SME | Severe Myoclonic Epilepsy
| Others |
| SME | Shape Memory Effect
| Others |
| SME | Shivamogga
| Others |
| SME | Shopping Made Easy
| Others |
| SME | Short Message Encryption
| Others |
| SME | Short Message Entity
| Others |
| SME | Siebel Market Enterprises
| Others |
| SME | Signaling Message Encryption
| Others |
| SME | Signature Micro Engine
| Others |
| SME | Significant Medical Event
| Others |
| SME | Significant Military Equipment
| Others |
| SME | Simple Menu Entry
| Others |
| SME | Sistema Monetario Europeo
| Others |
| SME | Situational Method Engineering
| Others |
| SME | Sloppy Meat Eater
| Others |
| SME | Slow Maxillary Expansion
| Others |
| SME | SM Entertainment
| Others |
| SME | Small and Medium Enterprise
| Others |
| SME | Small and Medium Enterprises
| Others |
| SME | Small and Medium Sized Enterprises
| Others |
| SME | Small and Medium-sized Enterprises
| Others |
| SME | Small And Mediumsized Enterprises
| Others |
| SME | Small and Micro Enterprises
| Others |
| SME | Small Medium Enterprise
| Others |
| SME | Small Medium Enterprises
| Others |
| SME | Small or Medium Enterprise
| Others |
| SME | Small or Medium Entreprise
| Others |
| SME | Small to Medium Enterprise
| Others |
| SME | Small to Medium Enterprise (SME) Server
| Others |
| SME | SmelterCoin
| Others |
| SME | Socialist Market Economy
| Others |
| SME | Society for Mining, Metallurgy, and Exploration
| Others |
| SME | Society of Manufacturing Engineers
| Others |
| SME | Society of Manufaturing Engineers
| Others |
| SME | Society of Mechanical Engineers
| Others |
| SME | Society of Men Engineers
| Others |
| SME | Sofia Music Enterprises
| Others |
| SME | Solar Mesosphere Explorer
| Others |
| SME | Somatic Mutational Event
| Others |
| SME | Sony Media Entertainment
| Others |
| SME | Sony Music Entertainment
| Others |
| SME | Spectroscopy Made Easy
| Others |
| SME | Standard Metropolitan Enterprises
| Others |
| SME | Standard-Model Extension
| Others |
| SME | State Medical Examiner
| Others |
| SME | State Museum of Ethnography
| Others |
| SME | State of Mississippi Entrepreneurs
| Others |
| SME | Stenotrophomonas Multiple Efflux
| Others |
| SME | Stepping Motor Electronics
| Others |
| SME | Storage Made Easy
| Others |
| SME | Storage Management Engine
| Others |
| SME | Storage Media Encryption
| Others |
| SME | Strange Martian Entity
| Others |
| SME | Strategic Management Energy
| Others |
| SME | Structural Mechanical Environment
| Others |
| SME | Structure Mapping Engine
| Others |
| SME | Subacute Measles Encephalitis
| Others |
| SME | Subject Matter Expert
| Others |
| SME | Subject Matter Experts
| Others |
| SME | Subject-Matter Expert
| Others |
| SME | Subsequent Memory Effect
| Others |
| SME | Success Maker Enterprise
| Others |
| SME | Sun Microelectronics
| Others |
| SME | Sunflower Methyl Ester
| Others |
| SME | Superior Medical Equipment
| Others |
| SME | Sustaining Membership Enrollment
| Others |
| SME | Synchronous Modem Eliminator
| Others |
| SME | System Management Entity
| Others |
| SME | System Module Expert
| Others |
| SME | Systems Management Enterprises, Inc.
| Others |