| SISC | Schedules Information Standards Committee 
| Others |
| SISC | Seattle Innovation Start up Competition
| Others |
| SISC | Second Interpreter of Scheme Code
| Others |
| SISC | Security Income Status Code
| Others |
| SISC | Security Industry Standards Council
| Others |
| SISC | Self Insured Schools of California
| Others |
| SISC | Simple Instruction Set Computer
| Others |
| SISC | Simulation Interoperability Standards Committee
| Others |
| SISC | Sindicatul Studentilor Din Cibernetica
| Others |
| SISC | Single Instruction Set Computer
| Others |
| SISC | Sistema Inteligente de Seleccion de Combustible
| Others |
| SISC | SMils International Summer Camps
| Others |
| SISC | Southeast Indian Studies Conference
| Others |
| SISC | Southern IN Sports Center
| Others |
| SISC | Southern Indiana Sports Center
| Others |
| SISC | Specialist Industrial Services Company
| Others |
| SISC | Stacked Interpretable Sequencing Cells
| Others |
| SISC | Stewardship Index For Specialty Crops
| Others |
| SISC | Strategic Initiatives Steering Committee
| Others |
| SISC | Student Information and Services Center
| Others |
| SISC | Student Involvement the Student Center
| Others |
| SISC | Studies in Slavic Cultures
| Others |
| SISC | Syracuse Indoor Sports Center
| Others |