| R&DO | Research and Development Operations (MSFC) 
| Others |
| RDO | Rabi Detuning Oscil
| Others |
| RDO | Race Day ONLY
| Others |
| RDO | Race Day Optimised
| Others |
| RDO | Race Day Optimized
| Others |
| RDO | Radio Down Octopus
| Others |
| RDO | Radio Transmission from Downed aircraft
| Others |
| RDO | Radiological Defense Officer
| Others |
| RDO | Rampage Data Object
| Others |
| RDO | Rapid Decisive Operations
| Others |
| RDO | Raster Data Object
| Others |
| RDO | Raster Document Object
| Others |
| RDO | Rate Distortion Optimization
| Others |
| RDO | Rate-Distortion Optimization
| Others |
| RDO | Red Dot Optics
| Others |
| RDO | Redemption Data Objects
| Others |
| RDO | Redistricting Data Office
| Others |
| RDO | Referenced Data Object
| Others |
| RDO | Regional Dental Officer
| Others |
| RDO | Regional Development Officers
| Others |
| RDO | Regional Development Organisation
| Others |
| RDO | Registered Dispensing Optician
| Others |
| RDO | Registered Dispensing Opticians
| Others |
| RDO | Regular Day Off
| Others |
| RDO | Regular Democratic Organization
| Others |
| RDO | Relational Database Operator
| Others |
| RDO | Relationship Dialogue Overhaul
| Others |
| RDO | Relativity Dynamic Object
| Others |
| RDO | Relished Day Off
| Others |
| RDO | Remote Data Object
| Others |
| RDO | Remote Data Objects
| Others |
| RDO | Request For Deployment Order
| Others |
| RDO | Required Days Out
| Others |
| RDO | Research Development Office
| Others |
| RDO | Resort Development Organisation
| Others |
| RDO | Resource Definition Online
| Others |
| RDO | Retard Delay Orifice
| Others |
| RDO | Revenue District Office
| Others |
| RDO | Revenue Divisional Officer
| Others |
| RDO | Reverse Dungeon Order
| Others |
| RDO | Risk Data Object
| Others |
| RDO | RNA-DNA oligonucleotide
| Others |
| RDO | Robust Design Optimization
| Others |
| RDO | Ron D Offutt
| Others |
| RDO | Ron D. Offutt, CEO of the R.D. Offutt Company
| Others |
| RDO | Rostered Day Off
| Others |
| RDO | RPM Distribution of OpenStack
| Others |
| RDO | Ruby Data Objects
| Others |
| RDO | Rude Drivel Only
| Others |
| RDO | Rugged Dissolved Oxygen
| Others |
| RDO | Ruota D'Oro
| Others |
| RDO | Rural Development Officer
| Others |
| RDO | Rural Development Organisation
| Others |