| OSL | Oaks School of Leadership 
| Others |
| OSL | Object Selection Language
| Others |
| OSL | Object Source Lighting
| Others |
| OSL | Object Support Library
| Others |
| OSL | Oblivion Sound Lab
| Others |
| OSL | Observed Significance Level
| Others |
| OSL | Ocean Sky Land
| Others |
| OSL | Ocean State Libraries
| Others |
| OSL | Oceanographic Systems Lab
| Others |
| OSL | Oceanographic Systems Laboratory
| Others |
| OSL | Off Scale Low
| Others |
| OSL | Office of Service Learning
| Others |
| OSL | Office of Space Launch
| Others |
| OSL | Office of Spiritual Life
| Others |
| OSL | Office of State Lands
| Others |
| OSL | Office of Student Life
| Others |
| OSL | OHBA Software Library
| Others |
| OSL | Oil Sands Lease
| Others |
| OSL | Oncology Systems Limited
| Others |
| OSL | Ontario Safety League
| Others |
| OSL | Ontario Soccer League
| Others |
| OSL | Open Shading Language
| Others |
| OSL | Open Software License
| Others |
| OSL | Open Source Lab
| Others |
| OSL | Open Source Law
| Others |
| OSL | Open Source Learning
| Others |
| OSL | Open Source License
| Others |
| OSL | Open Style Lab
| Others |
| OSL | Open Subscription License
| Others |
| OSL | Opening Swing Low
| Others |
| OSL | Operating on a Suspended License
| Others |
| OSL | Operating System Loader
| Others |
| OSL | Operation Solid Lives
| Others |
| OSL | Operation Starting Line
| Others |
| OSL | Operation Street Legal
| Others |
| OSL | Operation Support and Logistics
| Others |
| OSL | Optical Source Light
| Others |
| OSL | Optical Stimulated Luminescence
| Others |
| OSL | Optical Stimulating Luminescence
| Others |
| OSL | Optically Stimulated Luminescence
| Others |
| OSL | Optimization and Statistical Learning
| Others |
| OSL | Optimization Solutions Library
| Others |
| OSL | Optimization Subroutine Library
| Others |
| OSL | Optimus Services Limited
| Others |
| OSL | Orbiting Solar Laboratory
| Others |
| OSL | Order of Saint Luke
| Others |
| OSL | Oregon Short Line (Union Pacific Railroad)
| Others |
| OSL | Oregon State Library
| Others |
| OSL | Oriented Strand Lumber
| Others |
| OSL | Osl Setup Lite
| Others |
| OSL | Our Savior Loves
| Others |
| OSL | Our Savior Lutheran
| Others |
| OSL | Out of State License
| Others |
| OSL | Output Seal
| Others |
| OSL | Outsourced Sales Leadership
| Others |
| OSL | outstanding liabilities
| Others |
| OSL | Over Stay Leave
| Others |
| OSL | Over Stimulation Level
| Others |
| OSL | Overseas Service Learning
| Others |
| OSL | Oversize Load
| Others |
| OSL | The Order Of St Luke
| Others |