| OPAL | Obesity Prevention and Lifestyle 
| Others |
| OPAL | Object Process Alignment
| Others |
| OPAL | Object Programming Aggregate Layer
| Others |
| OPAL | Oblique Posterior Atraumatic Lumbar
| Others |
| OPAL | Oculo Plastic And Laser
| Others |
| OPAL | Of People And Land
| Others |
| OPAL | Office of Pluralism And Leadership
| Others |
| OPAL | Ohio Private Academic Libraries
| Others |
| OPAL | Oil Palm Adaptive Landscapes
| Others |
| OPAL | Olive Plantations of Australia, LTD.
| Others |
| OPAL | Omni Purpose Apparatus for LEP
| Others |
| OPAL | One People Absent Limits
| Others |
| OPAL | One People of Australia League
| Others |
| OPAL | Online Performance And Learning
| Others |
| OPAL | Online Permit Assistance and Licensing
| Others |
| OPAL | Online Personal Academic Librarian
| Others |
| OPAL | Online Presentation Access Library
| Others |
| OPAL | Open Air Labrotories
| Others |
| OPAL | Open Phone Abstract Library
| Others |
| OPAL | Open Phone Abstraction Library
| Others |
| OPAL | Open Physics Abstraction Layer
| Others |
| OPAL | Open Pool Australian Light
| Others |
| OPAL | Open Pool Australian Lightwater
| Others |
| OPAL | Open Process Adapter Library
| Others |
| OPAL | Open Process Automation Library
| Others |
| OPAL | Open Program Access License
| Others |
| OPAL | Operations Planning Administration and Logistics
| Others |
| OPAL | Optical Automatic Library
| Others |
| OPAL | Optimized Portable Application Libraries
| Others |
| OPAL | Orbiting Picosat Automated Launcher
| Others |
| OPAL | Orbiting Picosatellite Automated Launcher
| Others |
| OPAL | Orchestration and Provisioning Automation Library
| Others |
| OPAL | Oregon Parallel Logic
| Others |
| OPAL | Organic Products Acquisition and Logistics
| Others |
| OPAL | Organization for Positive Action and Leadership
| Others |
| OPAL | Organizing People Activating Leaders
| Others |
| OPAL | Our Plan Any Lot
| Others |
| OPAL | Outdoor Play And Learning
| Others |
| OPAL | Outer Planet Atmospheres Legacy
| Others |
| OPAL | Outstanding People and Leaders
| Others |
| OPAL | Outstanding Philanthropic Award For Leadership
| Others |
| OPAL | Outstanding Projects And Leaders
| Others |
| OPAL | Overseas Pharmaceutical Aid for Life
| Others |