| LES | Computer-based training LESson file 
| Others |
| LES | Laboratory Execution System
| Others |
| LES | Lake effect Snow
| Others |
| LES | Lake Erie Speedway
| Others |
| LES | Lambert-Eaton Syndrome
| Others |
| LES | LAN (Local Area Network) Emulation Server
| Others |
| LES | Lan Emulation Server
| Others |
| LES | Lan Extension Services
| Others |
| LES | Lancer es
| Others |
| LES | Land Earth Station
| Others |
| LES | Language for Embedded Systems
| Others |
| LES | Large Eddy Simu
| Others |
| LES | Large Eddy Simulation
| Others |
| LES | Launch Entry Suit
| Others |
| LES | Launch Equipment Shop
| Others |
| LES | Launch Escape System
| Others |
| LES | Law Enforcement Sensitive
| Others |
| LES | Lawrence Experimental Station
| Others |
| LES | le Baron Salon
| Others |
| LES | le Sabre
| Others |
| LES | Learning Environment Specialist
| Others |
| LES | Leave and Earnings Statement
| Others |
| LES | Leave and Earnings Statements
| Others |
| LES | LESion
| Others |
| LES | Lesotho
| Others |
| LES | Libre Echange Sur
| Others |
| LES | Licensing Executives Society
| Others |
| LES | Life Events Scale
| Others |
| LES | Light Emitting Sensor
| Others |
| LES | Lighted Entry System
| Others |
| LES | Limited Edition Scent
| Others |
| LES | Limited English Speaking
| Others |
| LES | Lincoln Electric System
| Others |
| LES | Lincoln Elementary School
| Others |
| LES | Lincoln Laboratories Experimental Satellite
| Others |
| LES | Line Encryption System
| Others |
| LES | Line Errored Second
| Others |
| LES | Linear Expenditure System
| Others |
| LES | Linux Enterprise Server
| Others |
| LES | Lipid Extract Surfactant
| Others |
| LES | Literacy and Essential Skills
| Others |
| LES | Literatures in English Section
| Others |
| LES | Liverpool Engineering Society
| Others |
| LES | Living Energy System
| Others |
| LES | Load Es Segment
| Others |
| LES | Loadable Ejection System
| Others |
| LES | Lobotomies for Every Student
| Others |
| LES | Local Enforcement Systems
| Others |
| LES | Local Enhanced Service
| Others |
| LES | Local enhanced services
| Others |
| LES | Local Excitatory State
| Others |
| LES | Locally Exponentially Stable
| Others |
| LES | Location Engine And Server
| Others |
| LES | Locker Evaluation System
| Others |
| LES | Logistic Execution System
| Others |
| LES | Logitech Entertainment System
| Others |
| LES | Loop Emulation Service
| Others |
| LES | Lotus Engine Simulation
| Others |
| LES | Louisiana Energy Services
| Others |
| LES | Louisiana Engineering Society
| Others |
| LES | Low End System
| Others |
| LES | Lower East Side
| Others |
| LES | Lower Esophageal Sphincter
| Others |
| LES | Lower OEsophageal Sphincter
| Others |