| ISSM | Ice Sheet System Model 
| Others |
| ISSM | Idle Speed Stepper Motor
| Others |
| ISSM | Ination Soft Systems Methodology
| Others |
| ISSM | Indiana Sub State Model
| Others |
| ISSM | Indonesian Students Scientific Meeting
| Others |
| ISSM | Information Security Systems Management
| Others |
| ISSM | Information Security Systems Manager
| Others |
| ISSM | Information System Security Manager
| Others |
| ISSM | Information Systems and Security Management
| Others |
| ISSM | Information Systems Security Manager
| Others |
| ISSM | Information Systems Security Monitor
| Others |
| ISSM | Institute for the Study of Security Markets
| Others |
| ISSM | Institute of Safety Systems Management
| Others |
| ISSM | Institute of Security and Safety Management
| Others |
| ISSM | Institute of Sports Sciences and Medicine
| Others |
| ISSM | Integrated Safegards Security Management
| Others |
| ISSM | Integrated Safeguards and Security Management
| Others |
| ISSM | Integrated Studies Special Major
| Others |
| ISSM | Interface for SWAN and SURF Models
| Others |
| ISSM | Interim Static Stability Model
| Others |
| ISSM | International Society for Sexual Medicine
| Others |
| ISSM | International Society For Strategic Marketing
| Others |
| ISSM | International Society for Subsurface Microbiology
| Others |
| ISSM | International Student Scholar Management
| Others |
| ISSM | International Student Services Management
| Others |
| ISSM | International Swaminarayan Satsang Mandal
| Others |