| ISCS | Associazione Italiana per la Simulazione con il Calcolatore 
| Others |
| ISCS | Idaho State Civic Symphony
| Others |
| ISCS | Illinois State Course System
| Others |
| ISCS | Impairment Study Capture System
| Others |
| ISCS | Imperial Sovereign Court of Spokane
| Others |
| ISCS | Income support
| Others |
| ISCS | Income Support Computer System
| Others |
| ISCS | Inner Sphere Cartography Society
| Others |
| ISCS | Institute for Security and Conflict Studies
| Others |
| ISCS | Institute for the Study of Contemporary Spirituality
| Others |
| ISCS | Integrated Secure Communications System
| Others |
| ISCS | Integrated Supply Chain Services
| Others |
| ISCS | Intelligence Specialist Senior Chief Petty Officer
| Others |
| ISCS | Intensive Social Communication Supports
| Others |
| ISCS | Interdisciplinary Symposium on Complex Systems
| Others |
| ISCS | International Sand Collectors Society
| Others |
| ISCS | International Security Control Solutions
| Others |
| ISCS | International Services and Communication Systems
| Others |
| ISCS | International Solar Cycle Studies
| Others |
| ISCS | International Student Community Service
| Others |
| ISCS | International Supply Chain Solutions
| Others |
| ISCS | International Symposium for Contemplative Studies
| Others |
| ISCS | Interstate Sprint Car Series
| Others |
| ISCS | Islamic Society of Colorado Springs
| Others |
| ISCS | Israel Stem Cell Society
| Others |
| ISCS | Italian Society for Computer Simulation
| Others |