| ISAC | Idol Star Athletic Competition 
| Others |
| ISAC | Idol Star Athletics Championships
| Others |
| ISAC | Illinois Student Assistance Commission
| Others |
| ISAC | Immune Stimulating Antibody Conjugate
| Others |
| ISAC | Immune System Activation Of Coagulation
| Others |
| ISAC | Immuno-solid phase allergen chip
| Others |
| ISAC | Immuno-Solid phase Allergy Chip
| Others |
| ISAC | Immuno-Solid phase Allergy Chip (
| Others |
| ISAC | In Situ Additive Construction
| Others |
| ISAC | Independent Schools Adventure Cruises
| Others |
| ISAC | Independent Sports Alliance of California
| Others |
| ISAC | Industry Sector Advisory Committee
| Others |
| ISAC | Information Sharing Analysis Center
| Others |
| ISAC | Information Sharing Analysis Centre
| Others |
| ISAC | Information Sharing and Analysis Center
| Others |
| ISAC | Information Sharing And Analysis Centers
| Others |
| ISAC | Information Systems Advisory Committee
| Others |
| ISAC | Institute for the Study of American Cultures
| Others |
| ISAC | Instruction Set Architecture C
| Others |
| ISAC | Instructor Signature to Add a Class
| Others |
| ISAC | Intelligence Sharing And Analysis Center
| Others |
| ISAC | Intelligent Secure Autonomic Controller
| Others |
| ISAC | Intelligent Soft Arm Control
| Others |
| ISAC | Intelligent System Analytic Computer
| Others |
| ISAC | Intelligent System For Aircraft Conflict
| Others |
| ISAC | International Schools Athletic Conference
| Others |
| ISAC | International Society for Advancement of Cytometry
| Others |
| ISAC | International Society for Analytical Cytology
| Others |
| ISAC | International Standard Accuracy Contest
| Others |
| ISAC | International Survivors Action Committee
| Others |
| ISAC | Internet Self Access Centre
| Others |
| ISAC | internet Speech Audio Codec
| Others |
| ISAC | Invasive Species Advisory Committee
| Others |
| ISAC | Iowa State Association of Counties
| Others |
| ISAC | Iprobe Surveillance Automation Communication
| Others |
| ISAC | Isa Client
| Others |
| ISAC | ISRO Satellite Centre
| Others |
| ISAC | Istituto di Scienze dell'Atmosfera e del Clima
| Others |