| IRL | I'm Really Lieing 
| Others |
| IRL | I'm Right Luy
| Others |
| IRL | Idea Realization Lab
| Others |
| IRL | Imaging Research Laboratory
| Others |
| IRL | Immigration Restriction League
| Others |
| IRL | Immunohaematology Reference Laboratory
| Others |
| IRL | Immunohematology Reference Laboratories
| Others |
| IRL | Immunohematology Reference Laboratory
| Others |
| IRL | Impotent Racers League
| Others |
| IRL | In Real Life
| Others |
| IRL | In the Right Lane
| Others |
| IRL | Independent Reading Level
| Others |
| IRL | Independent Records Ltd
| Others |
| IRL | Indian River Lagoon
| Others |
| IRL | Indigenous Rocket Launcher
| Others |
| IRL | Industrial Research Laboratory
| Others |
| IRL | Industrial Research Limited
| Others |
| IRL | Industrial Research Ltd
| Others |
| IRL | Indy Racing League
| Others |
| IRL | Initiating Reference Letter
| Others |
| IRL | Insane Racing League
| Others |
| IRL | Institute for Research on Learning
| Others |
| IRL | Institute for Rowing Leadership
| Others |
| IRL | Institute on Religious Life
| Others |
| IRL | Institutional Repository Library
| Others |
| IRL | Integrated Reader Lock
| Others |
| IRL | Integrated Rear Loader
| Others |
| IRL | Integration Readiness Level
| Others |
| IRL | Intelligent Retail Lab
| Others |
| IRL | Inter Regional League
| Others |
| IRL | Inter Repeater Link
| Others |
| IRL | Interactive Reader Language
| Others |
| IRL | Interface Requirement List
| Others |
| IRL | Intermediate Range Lander
| Others |
| IRL | Internal Representation Language
| Others |
| IRL | International Racing League
| Others |
| IRL | International Reading Literacy
| Others |
| IRL | International Requirement List
| Others |
| IRL | Internet Research Lab
| Others |
| IRL | Internet Resource Locator
| Others |
| IRL | Interscape Records Ltd
| Others |
| IRL | Inverse Reinforcement Learning
| Others |
| IRL | Investment Readiness Level
| Others |
| IRL | Ireland
| Others |
| IRL | Irl means: IN REAL LIFE. This is commonly used in video games and social media platforms.
| Others |
| IRL | Irrevelent Retirement League
| Others |
| IRL | is In Real Life
| Others |
| IRL | It's Ridiculously Lame
| Others |
| IRL | It's Right Left
| Others |
| IRL | The Icky Racing League
| Others |