| HPL | Hairpin Left 
| Others |
| HPL | Hairpin Links
| Others |
| HPL | Hamilton Public Library
| Others |
| HPL | Hapag Lloyd
| Others |
| HPL | Hapag Lloyd shipping company
| Others |
| HPL | Hartford Public Library
| Others |
| HPL | Hartmann Project Lines
| Others |
| HPL | Hearthstone Pro League
| Others |
| HPL | Helferich Patent Licensing
| Others |
| HPL | Henrietta Public Library
| Others |
| HPL | Heterogeneous Programming Library
| Others |
| HPL | Hewlett-Packard LaserJet printer
| Others |
| HPL | Hewlett-Packerd LaserJet Vector graphics file
| Others |
| HPL | High Performance Ladder
| Others |
| HPL | High Performance Lanes
| Others |
| HPL | High Performance Leadership program
| Others |
| HPL | High Performance Linpack
| Others |
| HPL | High Performance Logic
| Others |
| HPL | High Performance Lubricants
| Others |
| HPL | High Power Laser
| Military, Defence, Energy, Hardware |
| HPL | High Pressure Laminate
| Others |
| HPL | High Pressure Laminates
| Others |
| HPL | High Pressure Lanes
| Others |
| HPL | High Pressure Liquid
| Others |
| HPL | Hindustan Prefab Limited
| Others |
| HPL | Home Phone Lan
| Others |
| HPL | Horn Point Laboratory
| Others |
| HPL | Hot-electron Photo-Luminescence
| Others |
| HPL | Hours Per Level
| Others |
| HPL | Houston Paintball League
| Others |
| HPL | Houston Public Library
| Others |
| HPL | Howard Phillips Lovecraft
| Others |
| HPL | Hp Laboratories
| Others |
| HPL | Human Parotid Lysozyme
| Others |
| HPL | Human Performance Lab
| Others |
| HPL | Human Performance Laboratory
| Others |
| HPL | Human Photonics Laboratory
| Others |
| HPL | Human placental lactogen
| Others |
| HPL | Human Propulsion Laboratories
| Others |
| HPL | Huntington Public Library
| Others |
| HPL | Hydraulic Plug
| Others |
| HPL | Hydraulic Pump and Lift
| Others |
| HPL | Hydroplaning
| Others |
| HPL | Hypotonic Pharmacological Lip
| Others |