| COSMIC | Catalog Of Somatic Mutations In Cancer 
| Others |
| COSMIC | Catalogue of Somatic Mutations in Cancer
| Others |
| COSMIC | Center of Science and Mathematics in Context
| Others |
| COSMIC | Coherent Optical System of Modular Imaging Collectors
| Others |
| COSMIC | Common Software Measurement Consortium
| Others |
| COSMIC | Common Systems Main Interconnection
| Others |
| COSMIC | Constellation Observing System for Meteorology Ionosphere and Climate
| Others |
| COSMIC | NATO (North Atlantic Treaty Organization) Security Classification Category
| Others |