| CISO | Career Is Surely Over 
| Others |
| CISO | Certified Information Security Officer
| Others |
| CISO | Chief Information Security Officer
| Others |
| CISO | Chief Information Stupid Octopus
| Others |
| CISO | Clinical Investigations Support Office
| Others |
| CISO | College and Institute Student Outcomes
| Others |
| CISO | Computer Information Systems Organization
| Others |
| CISO | Computer Investigative Support Officer
| Others |
| CISO | Cook Islands Statistics Office
| Others |
| CISO | Corporate Information Security Office
| Others |
| CISO | Council of International Student Organizations
| Others |
| CISO | Counter-Intelligence Staff Officer
| Others |
| CISO | Criminal Intelligence Service Ontario
| Others |
| CISO | Crisis Induced Sacrificial Offering
| Others |