| CIRS | Celestial Intermediate Reference System 
| Others |
| CIRS | Center for International and Regional Studies
| Others |
| CIRS | Center for Intervention Research in Schools
| Others |
| CIRS | Center Information Retrieval System
| Others |
| CIRS | Center Information Retrieval System (CDRH)
| Others |
| CIRS | Centralized Interpreter Referral Service
| Others |
| CIRS | Centre for Innovation in Regulatory
| Others |
| CIRS | Centre for Interactive
| Others |
| CIRS | Centre for Interactive Research on Sustainability
| Others |
| CIRS | Centre for Interactive Research on Sustainability (UBC)
| Others |
| CIRS | Centre International de Recherche Scientifique
| Others |
| CIRS | Certified Information Reporting Specialist
| Others |
| CIRS | Chemical Inspection and Regulation Service
| Others |
| CIRS | Chinmaya International Residential School
| Others |
| CIRS | Chronic Inflammatory Response Sydrome
| Others |
| CIRS | Chronic Inflammatory Response Syndrome
| Others |
| CIRS | Coastal Interceptor Relief Sewer
| Others |
| CIRS | Combined Incident Reporting Software
| Others |
| CIRS | Community Information and Referral Services
| Others |
| CIRS | Cultural Institutions Retirement System
| Others |
| CIRS | Currency Interest Rate Swap
| Others |