| CCLE | Cancer Cell Line Encyclopedia 
| Others |
| CCLE | Center for Cognitive Liberty & Ethics
| Others |
| CCLE | Center for Cognitive Liberty Ethics
| Others |
| CCLE | Center for Community Learning and Enrichment
| Others |
| CCLE | Center for Continuing Legal Education
| Others |
| CCLE | CheckPoint Certified Licensing Expert
| Others |
| CCLE | Christian Copyright Licensing (Europe) Ltd
| Others |
| CCLE | Chronic cutaneous lupus erythematosus
| Others |
| CCLE | Collectif contre les Expulsions
| Others |
| CCLE | Collectif contre les Expulsions (French: Collective against Evictions; Belgium)
| Others |
| CCLE | Commission on Continuing Legal Education
| Others |
| CCLE | Consortium for Classical and Lutheran Education
| Others |
| CCLE | Counter Clockwise Lead End motor Rotation
| Others |
| CCLE | Creating a Collaborative Learning Environment (University of Wisconsin)
| Others |