| SAFC | Sunderland Association Football Club 
| Others |
| SAFC | Super Air Flow Converter
| Others |
| SAFC | Super Air Fuel Controller
| Others |
| SAFCA | Societe Africaine de Credit Automobile
| Others |
| SAFCEI | South African Faith Communities' Environmental Institute
| Others |
| SAFCS | Small Arms Fire Control System
| Others |
| SAFD | San Antonio Fire Department
| Others |
| SAFD | San Antonio Fire Department's
| Others |
| SAFD | San Antonio Folk Dancers
| Others |
| SAFD | Schizophrenic AFfective Disorder
| Others |
| SAFD | Serial ATA Flash Drive
| Others |
| SAFD | Society of American Fight Directors
| Others |
| SAFD | St Anna Fire Department
| Others |
| SAFD | Statistical Analysis of Fatigue Data
| Others |
| SAFD | Statistical Analysis of Fuzzy Data
| Others |
| SAFD | Stirring As Foam Disruption
| Others |
| SAFD | Systems Anomaly and Failure Detection
| Others |
| SAFE | A Safer Australia For Everyone
| Others |
| SAFE | Alternatives for Everyone
| Others |
| SAFE | Safe Affordable Fission Engine
| Others |
| SAFE | Safe Alternatives For Employees
| Others |
| SAFE | Safe And Friendly Environment
| Others |
| SAFE | Safe Automotive Software Architecture
| Others |
| SAFE | Safe, Active, and Family Environment
| Others |
| SAFE | Safeguarding America For Everyone
| Others |
| SAFE | Safely Affected Felony Entry
| Others |
| SAFE | Safer Affordable Fuel Efficient
| Others |
| SAFE | Safety Abuse and Fraud Education
| Others |
| SAFE | Safety Advancement For Employees
| Others |
| SAFE | Safety and Farm Labor Vehicle Education
| Others |
| SAFE | Safety Assessment For Emergencies
| Others |
| SAFE | Safety Awareness Faith Empowerment
| Others |
| SAFE | Safety Awareness For Everyone
| Others |
| SAFE | Safety Awareness From Education
| Others |
| SAFE | Safety Awareness, Faith, and Empowerment
| Others |
| SAFE | Salvation Army Fellowship of Endeavour
| Others |
| SAFE | Samsung Approved for Enterprise
| Others |
| SAFE | San Andreas Fault Experiment
| Others |
| SAFE | San Diego Service Authority for Freeway Emergencies
| Others |
| SAFE | Santa Fe Sauce Viejo, Argentina
| Others |
| SAFE | Save A Family Environment
| Others |
| SAFE | Save Animals From Elimination
| Others |
| SAFE | Saving A Future Everyday
| Others |
| SAFE | Saving Animals From Euthanasia
| Others |
| SAFE | Saving Animals From Extinction
| Others |
| SAFE | Saving Antiquities for Everyone
| Others |
| SAFE | Schools Against Fearful Environments
| Others |
| SAFE | Scope Analyze Formulate Execute
| Others |
| SAFE | Scream Avoid Fight Escape
| Others |
| SAFE | Sears Anderson Fire Extinguisher
| Others |