| I/T | Intrathecal 
| Medical |
| I/V | Inlet Valve 
| Hardware |
| I03 | Information Object Oriented Obsidian 3 
| Computer Programming |
| I0M | I Owe Money 
| Finance |
| I18N | Indiana route 18 North 
| Route |
| I18N | Internationalization 
| Computer Programming, Marketing |
| I2 | Image Intensification 
| Technology |
| I2 | Internet 2 
| Internet |
| I2 | Ion Implant (also seen as II) 
| Technology |
| I23 | Fayette County Airport, Washington Court House, Ohio USA 
| Airport |
| I2A | Insights to Action 
| Technology, Analytics |
| I2A2 | Infrastructure for Identification Authentication and Authorization 
| Computing, Security |
| I2C | Information Copy Control 
| Computing |
| I2C | Infrastructure to Car 
| Technology, Transport |
| I2C | Intelligent Controller 
| Technology, Computing |
| I2C | Inter Integrated Circuit
| Others |
| I2C | Inter-Integrated Circuit 
| Technology |
| I2CEWS | Intelligence Information Cyber Electronic Warfare and Space 
| Military |
| I2G | Immune 2 Greed 
| Computing |
| I2I | Infrastructure to Infrastructure
| Others |
| I2L | Integrated Injection Logic 
| Electronics |
| I2L | Integrated Injector Logic
| Others |
| I2M | Idea to Market 
| Business, Entrepreneurship |
| I2M | Integrated Internet Marketing 
| Marketing |
| I2NSF | Interfaces to Network Security Functions 
| Computing |
| I2O | Intelligent Input Output
| Others |
| I2O | Intelligent Input/Output 
| Computing |
| I2OR | International Institute of Organized Research 
| Institute |
| I2P | Invisible Internet Project 
| Software |
| I2POS | Internet to Point of Sale 
| Sales |
| I2R | Imaging Infrared 
| Technology |
| I2S | Inter Ic Sound
| Others |
| I2S | Inter-IC Sound 
| Technology |
| I2SF | International Information Security Foundation 
| Education, Internet, Technology, Security |
| I2T | Image to Text 
| Technology |
| I2TL | Introduction to Transformer Losses
| Others |
| I2V | Infrastructure to Vehicle 
| Technology, Transport |
| I2V | Invisible to Visible 
| Technology, Transport |
| I2VC | Infrastructure to Vehicle Communication 
| Technology, Transport |
| I2W | Independent Double Wishbone 
| Hardware, Transport |
| i2z | Information Inquiry Independan2z
| Others |
| I3 | Interface source (Modula-3) 
| Programming Language |
| I300I | International 300mm Initiative
| Others |
| I3A | Indole-3-Acetonitrile 
| Chemistry, Chemical Compound |
| I3A | Installation Information Infrastructure Architecture 
| Military |
| I3A | International Imaging Industry Association 
| Organization |
| I3C | In Car Customer Communication 
| Technology, Transport |
| I3C | Innocenti Tre Cilindri 
| Transport |
| I3D | Interactive Three Dimensional 
| Technology |
| I3DL2 | Interactive Three Dimensional Audio Level Two
| Others |